IMidazo[1,2-a]pyridine-2-MethanaMine, N-Methyl-

IMidazo[1,2-a]pyridine-2-MethanaMine, N-Methyl- - Names and Identifiers

Name	IMIDAZO[1,2-A]PYRIDIN-2-YLMETHYL-METHYL-AMINE
Synonyms	AKOS B006886 ART-CHEM-BB B006886 N-methyl-Imidazo[1,2-a]pyridine-2-methanamine IMIDAZO[1,2-A]PYRIDIN-2-YLMETHYL-METHYL-AMINE Imidazo[1,2-a]pyridine-2-methanamine, N-methyl- IMidazo[1,2-a]pyridine-2-MethanaMine, N-Methyl- 1-(iMidazo[1,2-a]pyridin-2-yl)-N-MethylMethanaMine
CAS	193534-56-4

IMidazo[1,2-a]pyridine-2-MethanaMine, N-Methyl- - Physico-chemical Properties

Molecular Formula	C9H11N3
Molar Mass	161.2
Boling Point
Storage Condition	2-8°C(protect from light)

IMidazo[1,2-a]pyridine-2-MethanaMine, N-Methyl- - Introduction

IMIDAZO [1,2-a] PYRIDIN-2-YLMETHYL-METHYL-AMINE is an organic compound with the formula C11H10N4, which has the following properties:

1. Appearance: IMIDAZO [1,2-a] PYRIDIN-2-YLMETHYL-METHYL-AMINE is a white crystalline solid.

2. Solubility: It is soluble in polar solvents such as water, ethanol and dimethyl sulfoxide.

3. Chemical properties: it is alkaline, can react with acid to generate salts. It can also participate in the nitration reaction, oxidation reaction and ring formation reaction of aromatic amines.

IMIDAZO [1,2-a] PYRIDIN-2-YLMETHYL-METHYL-AMINE is mainly used in organic synthesis, the specific uses are as follows:

1. Catalyst: It is often used as a catalyst for cross-coupling reactions, such as Suzuki coupling reactions.

2. Drug synthesis: It is an important intermediate for the synthesis of some drugs and physiologically active substances. For example, it can be used to synthesize the anti-blood cancer drug Imatinib.

3. Dye synthesis: It can be used to synthesize dyes, such as pyrazolopyrrole fixing agent.

IMIDAZO [1,2-a] PYRIDIN-2-YLMETHYL-METHYL-AMINE can be prepared by the following methods:

1. Application of metal catalyzed reaction synthesis: through metal catalyst, such as palladium catalysis, the aniline compound and β-keto acid compound under appropriate conditions, the target product is generated.

2. Synthesis of Nitrogen Heterocyclic Compounds: 1,2-dichloroethane and N-methylimidazole are reacted to generate 1,2-dichloro-5-methylimidazole, and then reacted with pyridine Dione to generate IMIDAZO[1,2-A]PYRIDIN-2-YLMETHYL-METHYL-AMINE.

When using and handling IMIDAZO [1,2-a] PYRIDIN-2-YLMETHYL-METHYL-AMINE, you need to pay attention to the following safety information:

1. Avoid contact with skin and eyes: protective gloves, protective glasses and protective mask is necessary.

2. Avoid inhalation and intake: During operation, protective masks and protective workbenches should be used to ensure good ventilation conditions.

3. Storage and transportation: the compound should be stored in a dry, ventilated and dark place, avoid contact with oxidants, acids, alkalis and other substances.

Please operate with caution and follow the correct laboratory operating procedures and safe operating instructions.

Last Update：2024-04-09 21:21:28